Andrew Wyatt works with CEOs, chairs and PE and VC-backed boards on the moves that decide the next stage.
Lotus to IBM $3.5B · Paragon to Phone.com $500M · Apertio to Nokia $240M · Clearswift to Lyceum $50M
Boards do not need more material. They need a catalyst. The one input that dissolves the noise and leaves the room with a decision the company can act on. Every Ortent engagement is built around that single act of clarification: drop in, dissolve the complexity, leave the call.
// THE ORTENT PRINCIPLEPick the shape that matches the decision on the table.
One question, one board-ready answer. Fixed scope, fixed timeline.
Read more → One quarterFull commercial and operating read. Twenty questions against evidence.
Read more → OngoingStanding counsel to CEO or Chair. Monthly cadence, defined scope.
Read more → Executive seatPart-time commercial leadership through the scale-up years.
Read more → Board seatBoard contribution grounded in operator experience, not observer commentary.
Read more →
"Andrew is one of the few SaaS leaders I've worked with who genuinely understands how to build commercial relationships at the intersection of life sciences and software. He thinks like a partner, not a vendor, which is exactly what makes the work move."
"Andrew's one of those rare breeds who really understands technology, but also has the listening and strategic skills to read customers and markets. Smart guy."
"Andrew approaches AI-related commercial, legal, and privacy risks with a deep understanding and the strategic insight of a board member. He excels at balancing the potential for revenue growth and competitive advantage with the necessary regulatory compliance and risk management, all while communicating these complexities with ease."
"Andrew is one of the sharpest commercial operators I've worked with, and a charismatic leader people love to work for. He sees the GTM motion and the customer simultaneously, and he builds partner ecosystems that drive pipeline rather than just logo slides."
"Zifo and Sapio have collaborated closely for several years, working together to ensure seamless integration of the Sapio Platform with our Lab Data Automation Solution. By combining our expertise in scientific informatics services with Sapio's lab informatics solutions, we can provide our customers with a world-class approach to lab automation and further the adoption of AI in biotech and pharma."
"The partner program Andrew built at Sapio set a new bar for what life sciences software ecosystems can look like. He made it easy for global services partners like Cognizant to invest, deliver, and grow alongside the platform, which is rarer than it should be."
"Working with Andrew on the Sapio and Elsevier collaboration showed me what AI ecosystem thinking looks like in practice. He moves the conversation past 'how do we integrate?' and into 'how do our two products make each other more valuable?'. That design instinct is what separates a partnership that compounds from a logo on a slide."
Six artefacts a CEO or Chair can drop in front of their team and use. Free. No email capture.
Weekly on Substack and inside LinkedIn. Board-facing commentary on growth-stage SaaS, life sciences and the AI value gap.
Most partner programmes are four programmes pretending to be one. That conflation kills more partner revenue than the economics ever do. The guide sets out the four archetypes, the AI co-growth model, and how to measure a partner ecosystem that compounds rather than just adds logos to a slide.
Thirty years in B2B SaaS. Four exits: Lotus to IBM ($3.5B), Paragon Software to Phone.com ($500M), Apertio to Nokia ($240M), Clearswift to Lyceum Capital ($50M).
Most recently Chief Growth Officer at Sapio Sciences and Sigmatic Sciences. Before Sapio, Chief Operating Officer at Lumeon. Ortent is the vehicle for advisory, board and fractional executive work with growth-stage life sciences and AI SaaS.
For a board, advisory or fractional engagement, or a working call on the next stage, email directly. Thirty minutes is usually enough to test fit.
Book a 30-minute intro call